SCIENTIFIC AGENDA DOWNLOAD THE PDF PROGRAM
= Invited short talks (ASR reserves the right to substitute talks)
SATURDAY JULY 8 |
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12:00 - 5:30 PM |
Registration Desk Open |
Cliff Ballroom Lobby |
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12:00 - 3:00 PM |
Poster Set Up |
Event Tent |
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2:00 – 3:00 PM |
Early Career Mentoring Session (Pre-Meeting) Moderator: Stacey Gilk, University of Nebraska Medical Center Panelists:
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Cliff Ballroom I |
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3:00 – 3:05 PM |
Welcome & Introductions Joao Pedra, ASR President |
Cliff Ballroom I |
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3:05 – 4:50 PM |
Session 1: Anaplasma and Ehrlichia - Vector Transmitted, Vacuolar Bacterial Manipulations Session Chair: Adela Oliva Chavez, Texas A&M University |
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3:05 PM |
1A. Plenary Overview: Immune system optimization in a variable world - Ann Thomas Tate, Vanderbilt University |
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3:35 PM |
1B. Keynote: New insights into Anaplasma phagocytophilum pathogenesis: exploitation of multi-vesicular body biogenesis and sphingolipid signaling - Jason Carlyon, Virginia Commonwealth University |
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4:05 PM |
1C. Mechanism of action of a novel in vivo virulence factor of Ehrlichia - EHF0962 - Rory Chien, The Ohio State University |
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4:20 PM |
1D. Anaplasma phagocytophilum AipA interacts with CD13 to elicit signaling that benefits host cell invasion - Mary Clark Lind, Virginia Commonwealth University |
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4:35 PM |
1E. Anaplasma phagocytophilum-infected neutrophils reverse-transmigrate dermal microvascular barriers to disseminate in a 3D model - Nathaniel Nenortas, Uniformed Services University |
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4:50 – 5:00 PM |
BREAK |
Ballroom I Lobby |
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5:00 – 5:30 PM |
ASR Lecture: The inequity of infectious disease burden and outcomes in global health Guy Palmer, Washington State University |
Cliff Ballroom I |
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5:30 – 7:00 PM |
WELCOME RECEPTION |
Golden Cliff |
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Dinner (on your own at resort) |
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SUNDAY JULY 9 |
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| 7:00 - 8:00 AM |
Continental Breakfast |
Golden Cliff |
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7:00 - 12:00 PM |
Registration Desk Open |
Ballroom I Lobby |
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8:00 – 9:45 AM |
Session 2: Vector Contribution to Rickettsial Pathogenesis Session Chair: Kathryn Reif, KSU |
Cliff Ballroom I |
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8:00 AM |
2A. Plenary Lecture: Genome-wide pooled CRISPR screen in arthropod cells - Norbert Perrimon, HHMI/Harvard University |
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8:30 AM |
2B. Keynote Speaker: Acquired Tick Resistance - Erol Fikrig, Yale University |
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9:00 AM |
2C. Ehrlichial manipulation of its vector, Ixodes scapularis - Joseph Aspinwall, NIH |
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9:15 AM |
2D. Effect of Anaplasma spp. transmission on neutrophil migration and collagen structure - Adela Oliva Chavez, Texas A&M University |
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9:30 AM |
2E. Stressed for success: how the unfolded protein response in Ixodes scapularis intertwines with pathogen survival - Kaylee Vosbigian, Washington State University |
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9:45 – 10:15 AM |
REFRESHMENT BREAK |
Ballroom I Lobby |
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10:15 – 12:00 PM |
Session 3: Tick-borne Spotted Fever Group Rickettsia Session Chair: Rebecca Lamason, MIT |
Cliff Ballroom I |
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10:15 AM |
3A. Plenary Lecture: The molecular basis for Chlamydia-mediated remodeling of epithelial in the upper genital tract - Raphael Valdivia, Duke University |
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10:45 AM |
3B. Keynote: Manipulation of host cell structures by spotted fever group Rickettsia - Matthew Welch, UC Berkeley |
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11:15 AM |
3C.Host glutathione is required for proper septation, actin-based motility, and virulence of Rickettsia parkeri - Thomas Burke, UC Irvine |
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11:30 AM |
3D. Quantitative analysis of morphogenesis and growth dynamics in Rickettsia parkeri - Wanda Figueroa-Cuilan, The Johns Hopkins University |
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11:45 AM |
3E. New biology from an old antigen: a role for the 17kDa surface lipoprotein in rickettsial cell envelope maintenance - Brandon Sit, MIT |
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12:00 – 1:00 PM |
Business Meeting |
Cliff Ballroom I |
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1:00 – 3:00 PM |
Poster Session I & Lunch (included) |
Event Tent |
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3:00 – 6:30 PM |
Free Time / Optional Alpine Activities |
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6:30 - 9:00 PM |
ASR DINNER (included w/registration fee) |
The Summit |
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Meet at the Aerial Tram base for the tram ride to the Summit. Trams leave promptly at 6:00 / 6:20 / 6:40 |
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MONDAY JULY 10 |
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| 7:00 - 8:00 AM |
Continental Breakfast |
Golden Cliff |
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7:00 - 2:00 PM |
Registration Desk Open |
Ballroom I Lobby |
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8:00 – 9:45 AM |
Session 4: Host Immune Responses Against Rickettsial Agents Session Chair: Sean Riley |
Cliff Ballroom I |
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8:00 AM |
4A. Plenary Lecture: Impact of immunity to vector arthropod bites on pathogen transmission - Jesus Valenzuela, NIH |
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8:30 AM |
4B. Keynote: Dysregulated Innate and Cellular Immunity during Acute Orientia tsutsugamushi Infection - Lynn Soong, UTMB |
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9:00 AM |
4C. Reversion of cbu0533 mutation in Coxiella burnetii Nine Mile II RSA439, clone 4 results in LPS elongation and increased virulence in a guinea pig model of infection - Carrie Long, NIH |
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9:15 AM |
4D. The role of polysaccharide synthesis operon in modulating Rickettsia-endothelial cell interactions - Smruti Mishra, Stonybrook University |
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9:30 AM |
4E. Unveiling a new strategy of Rickettsia: APRc moonlighting as an evasin by recruiting human complement regulator C4BP - Isaura Simoes, Biocant, Portugal |
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9:45 – 10:15 AM |
REFRESHMENT BREAK |
Ballroom I Lobby |
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10:15 – 12:00 PM |
Session 5: Cell Biology of Infection Session Chair: Stacey Gilk, University of Nebraska Medical Center |
Cliff Ballroom I |
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10:15 AM |
5A: Plenary Lecture: How co-morbidities affect disseminated infection with non-Typhi Salmonella - Renee Tsolis, UC Davis |
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10:45 AM |
5B: Keynote: The cell biology and pathogenesis of Orientia tsutsugamushi - Jeanne Salje, University of Cambridge |
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11:15 AM |
5C. Bacterial dissemination and protective innate immune responses in an intradermal inoculation mouse model of scrub typhus - Yuejin Liang, UTMB |
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11:30 AM |
5D. Mapping the Chlamydia trachomatis conventional type III secreted effector – host interactome - Brianna Steiert, University of Iowa |
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11:45 AM |
5E. The rickettsial effector, RickA, contributes to cell-to-cell spread - Joseph Tran, UC Berkeley |
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12:00 – 2:00 PM |
Poster Session 2 & Lunch (included) |
Event Tent |
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2:00 PM – 3:45 PM |
Session 6: Epidemiology, Diagnostics, and Vaccine Development Session Chair: Joao Pedra, University of Maryland SOM |
Cliff Ballroom I |
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2:00 PM |
6A: Plenary Lecture: Novel ecological features of emerging Rocky Mountain spotted fever at the US-Mexico border - Janet Foley, UC Davis |
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2:30 PM |
6B. Keynote: Evolution of Ehrlichia Vaccine Development in the 21st Century - Jere McBride, UTMB |
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3:00 PM |
6C. Modified live Anaplasma marginale vaccine developed by targeted mutagenesis stimulates protective immunity against wild type infection from infected tick feeding - Jonathan Ferm, University of Missouri |
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3:15 PM |
6D. Serologic and molecular testing for the diagnosis of Rickettsia, Anaplasma, and Ehrlichia infections in individuals in Maryland - Kristin Mullins, University of Maryland |
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3:30 PM |
6E. Adjuvanting Coxevac® with QuilA® skews Coxiella burnetii-induced inflammatory responses towards a sustained Th1-CD8+-mediated activation and increases protection in an experimental goat model - Sara Tomaiuolo, Sciensano, Belgium |
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TUESDAY JULY 11 |
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| 7:00 - 8:00 AM |
Continental Breakfast |
Golden Cliff |
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7:00 - 12:00 PM |
Registration Desk Open |
Ballroom I Lobby |
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8:00 – 9:45 AM |
Session 7: Coxiella Biology and Pathogenesis Session Chair: Shawna Reed, Quinnipiac University |
Cliff Ballroom I |
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8:00 AM |
7A: Plenary Lecture: Conserved strategies to attack the replication niche of intravacuolar pathogens - Ralph Isberg, Tufts University |
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8:30 AM |
7B. Keynote: Establishing the intracellular niche during Coxiella infection - Stacey Gilk, University of Nebraska Medical Center |
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9:00 AM |
7C. Host inducible LD-transpeptidase dependent cell envelope remodeling is a major determinant of developmental morphogenesis in Coxiella burnetii and Legionella pneumophila - Kelsi Sandoz, Cornell University |
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9:15 AM |
7D. Manipulation of TNFα signaling by Coxiella burnetii during infection - Chelsea Osbron, Washington State University |
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9:30 AM |
7E. Coxiella burnetii modulates host pro-inflammatory and microRNA response - Rahul Raghavan, University of Texas San Antonio |
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9:45 – 10:15 AM |
REFRESHMENT BREAK |
Ballroom I Lobby |
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10:15 – 12:00 PM |
Session 8: Vector-Microbe-Host Interactions Session Chair: Kelsi Sandoz, Cornell University |
Cliff Ballroom I |
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10:15 AM |
8A: Plenary Lecture: A Wolbachia secreted effector disrupts host endocytosis - Irene Garcia Newton, Indiana University |
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10:45 AM |
8B. Keynote: Prospects for a live-attenuated rickettsial vaccine - Ulrike Munderloh, University of Minnesota |
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11:15 AM |
8C. Regulation of the wound healing response at the tick-skin interface - Luisa Valencia, University of Maryland School of Medicine |
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11:30 AM |
8D. Targeted tag mutagenesis employed in studies to define Ehrlichia translocated factor-1 (Etf-1) interactions with host cellular proteins - Dominica Genda, University of Missouri |
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11:45 AM |
8E. National MALDI-TOF MS database of Dermacentor variabilis and Dermacentor similis - Maria Galletti, CDC |
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12:00 – 12:15 PM |
Closing Remarks by the 2024 President |
Cliff Ballroom I |